Long Term Survival

Survival following pancreaticoduodenectomy for periampullary carcinoma is highly dependent on the tumor's site of origin. For instance, survival after resection of distal bile duct, ampullary, and duodenal AC has always been significantly greater that that for pancreatic AC, with 5-year survival rates ranging from 30 to 50% (Yeo et al, 1997) In contrast, 5-year survival rates for patients with AC in the head of the pancreas managed by pancreaticoduodenectomy have been reported to reach 21%. A number of variables have been evaluated by univariate and multivariate analyses in an attempt to identify other factors predictive of long-term survival. Tumor characteristics found by most investigators to be important predictors of survival include tumor size, lymph node status, and resection margin status.

Survival following pancreaticoduodenectomy for periampullary lesions that are not AC are strongly dependent on the histology and biologic behavior of the primary lesion resected. Benign lesions that are completely resected generally result in very high long-term survival. Neuroendocrine tumors of the pancreas that are resected may have a variable and somewhat indolent course.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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