Management of Mild to Moderately Severe C difficileAssociated Diarrhea

In patients with suspected C. difficile-induced diarrhea, the first priority is to discontinue the inciting antibiotic, if it is safe to do so. Up to 25% of all C. difficile infections will resolve spontaneously upon the discontinuation of antibiotics. However, patients with more severe symptoms should be treated with specific C. difficile-directed antibiotics. The two most commonly used agents are metronidazole and

Mild Diarrhea

FIGURE 51-3. Colon specimen from a patient with severe, refractory Clostridium difficile diarrhea and colitis. Characteristic raised adherent yellow plaques that vary in size from 2 to 10 mm are visible on the colonic mucosa (arrow 1). In some areas, coalescing pseudomembranes are visible (arrow2). There is nonspecific erythema of the colonic mucosa between the pseudomembranes (arrow3). Reproduced with permission from Kelly CP, Pothoulakis C, Lamont JT. Clostridium difficile colitis. N Engl J Med 1994;330:257-62.

FIGURE 51-3. Colon specimen from a patient with severe, refractory Clostridium difficile diarrhea and colitis. Characteristic raised adherent yellow plaques that vary in size from 2 to 10 mm are visible on the colonic mucosa (arrow 1). In some areas, coalescing pseudomembranes are visible (arrow2). There is nonspecific erythema of the colonic mucosa between the pseudomembranes (arrow3). Reproduced with permission from Kelly CP, Pothoulakis C, Lamont JT. Clostridium difficile colitis. N Engl J Med 1994;330:257-62.

vancomycin. The advantages and disadvantages of each are described below. In addition to metronidazole and van-comycin, bacitracin, teicoplanin, fusidic acid and colestipol have been used to treat C. difficile infections.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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