Further support for the diagnosis of CIP, and clues to the possible underlying etiology, can often be obtained from intestinal manometry. Esophageal manometry will reveal abnormalities in esophageal motility in approximately 80% of patients with pseudo-obstruction. Sullivan and colleagues demonstrated incomplete LES relaxation after a swallow, as well as absence of peristalsis after both a swallow and balloon distension of the upper esophagus. Studies with antroduodenal manometry may also reveal characteristic motility abnormalities. This may include one or more of the following:

1. Aberrant propagation and/or configuration of interdigestive migrating motor complexes

2. Bursts of nonpropagated phasic pressure activity in the fasting and fed states

3. Sustained (> 30 min) and intense phasic pressure activity occurring in a segment of intestine while normal or reduced activity is noted simultaneously at other levels of the intestine

4. Inability of the ingested meal to change fasting intestinal activity into a fed pattern (Stanghellini et al, 1987).

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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