Table 71-1 provides an overview of the pathophysiological mechanisms and conditions associated with diarrhea in diabetes. The mechanisms of chronic diarrhea in diabetes are incompletely understood. However, several commonly
Table 71-1 Mechanisms, Concomitant Conditions, and Clinical Characteristics of Diarrhea in Diabetes Mellitus
Pathophysiological Associated Mechanism Disease
SB dysmotility Colonic dysmotility Decreased a-2-adrenergic tone in enterocytes
Constipation or diarrhea
Anorectal dysfunction Sensory neuropathy IAS-sympathetic EAS-pudendal neuropathy
Diarrhea or incontinence
encountered mechanisms for diarrhea in patients with diabetes should be considered. Diarrhea may result from intake of medications or the excessive use of dietetic foods that contain sorbitol as a sweetener. Autonomic neuropathy (Vinik et al, 2003) or diseases associated with diabetes, such as celiac disease, may be the underlying causes of chronic diarrhea.
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Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...