Menetriers Disease

Menetrier's disease is extremely rare, characterized by a "growth disorder" in which the gastric pits (foveolae) become elongated, cystic, and replace oxyntic glands—a hypertrophic gastropathy with variable amounts of inflammatory infiltrate. Menetrier's carries an increased risk of cancer (Vandenborre et al, 1998). Admonitions are generally given in case reports of these cancers to do periodic surveillance. This is easier said than done because the mucosa consists of a forest of thick polypoid folds in the gastric body. When first encountered, I look carefully for any lesions that stand out in terms of size or color. Then I biopsy map the gastric body and fundus. Thereafter I repeat this practice yearly, recognizing that finding early cancer amongst polypoid folds is a great challenge. The condition is so rare that it is not likely that evidence-based guidelines will be forthcoming to help guide the practice of surveillance for cancer.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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