Percutaneous liver biopsy should be performed on all children with chronic HCV 3 years of age or older. If there is evidence of aggressive disease (piecemeal necrosis, periportal or lobular fibrosis) then therapy should be initiated with IFN 3 MU/m2 thrice weekly subcutaneously for 48 weeks in combination with ribavirin 15 mg/kg/d with a maximum daily dose of 1200 mg. If there is only mild disease, I suggest deferring treatment until results of the large scale multicenter trial described above are available and/or until more effective, less toxic therapies emerge.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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