The predominant clinical feature of advanced mesenteric vascular disease is the systemic sepsis that results initially from the loss of the mucosal barrier to bacteria and endotoxin from the lumen of the intestine itself. Probably because of the size of the bacterial inoculum and the dose of endotoxin, the sepsis engendered by intestinal ischemia may be particularly fulminant, especially at later stages of the disease. It is also remarkably resistant to antibiotics, probably because the process of inoculation continues until the underlying process has been reversed. It may be particularly devastating immediately after revascularization of an ischemic bowel segment by angioplasty vascular bypass or, more often, by reduction of strangulation. All patients suspected of having ischemic bowel disease should therefore be given high intravenous (IV) doses of broad spectrum antibiotics, including anaerobic coverage. Nevertheless, even the most vigorous antibiotic program provides only temporary support while definitive diagnostic studies and treatment are instituted.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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