Somatostatin Octreotide

Available evidence does not support the routine use of somatostatin or octreotide in acute NVUGIB. A subgroup analysis of investigator-blinded trials (eight studies) within a meta-analysis demonstrated that the efficacy of somato-statin for the prevention of recurrent bleeding was modest and was limited to peptic ulcer bleeding (Imperiale and Birgisson, 1997). The need for surgery did not differ significantly between the somatostatin group and the control group, nor did the difference in the blood transfusion requirements. Other studies (Lin et al, 1995; Coraggio et al, 1998) have shown similar efficacy compared to H2-receptor antagonists and less efficacy compared to endo-scopic therapy (Barkun et al, 2003).

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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