Virologic Assessment of Response

This is determined using the following key tests:

1. Baseline reference HCV RNA (viral titer and genotype) is best measured just before starting treatment to determine optimal treatment duration and regimen, and to establish a baseline to determine later treatment end-points.

2. Early virologic response can be assessed after 12 weeks of therapy. Failure to achieve a decline in HCV RNA levels of at least 2 logs by week 12 predicts an extremely low likelihood of a sustained virologic response with further treatment (negative predictive value = 98%).

3. End-of-treatment is performed at the end of the recommended course to determine whether viral response occurred during treatment.

4. Sustained virologic responses is performed at the end of 6 months of observation following completion of treatment, and appears to be the gold standard for long term loss of serum HCV RNA.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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