Delayed hypersensitivity

This type of reaction results from lymphocytes known as T cells, because of their derivation from the thymus, which react with antigen in the skin. The reaction is initiated by antigen attached to Langerhan's cells in the epidermis being transported to the paracortical area of the regional lymph node with the production of lymphocytes sensitised specifically for that antigen. There is also the production of interleukin which has a feedback effect in stimulating the production of more sensitised lymphocytes.

The reaction of the T lymphocytes in the epidermis results in the accumulation of macrophages and the release of inflammatory mediators.

Type III—circulating immune complexes

Type IV—delayed hypersensitivity

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

Get My Free Ebook


Post a comment