Types of allergic reaction

Allergic and other immune reactions may occur in the skin—the "immunological battleground of the body"—rather than involving internal organs. An acute vasculitis occurring in the skin is unpleasant and requires treatment but the same reaction occurring in the kidneys can be life threatening. The pattern of skin changes can indicate the type of immune process involved and also whether there is likely to be systemic involvement. The immune response of the skin is also used clinically in the tuberculin skin test to detect the level of immunity to tuberculosis. It is also the means of immunisation when an injection of inactivated organisms induces an immune response that protects the entire body.

The different types of immune reaction are all manifested in the skin as part of a normal response to pathogens or as an allergic reaction. The difference is expressed by the word "allergy", first used by Von Pirquet in 1906, derived from the Greek (a7o^ ev7ov), meaning literally "other work". In other words it is a response that is appropriate for pathogenic organisms such as a tubercle bacillus but is misdirected against a harmless substance such as a rubber glove or the metal of a watch strap buckle.

Immunological reactions are of four types—five if autoimmunity is counted—of responses mediated by antibodies known as the humoral response and one by the lymphocytes known as the cell mediated response.

How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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