Baclofen can be injected to reduce spasticity, but it is only available for injection into the spinal fluid using an implantable pump. Direct injection into the spinal fluid is used only as a test to evaluate the patient's response before implanting the pump. This device allows the baclofen to be delivered into the spinal fluid continuously. It is called intrathecal baclofen and is used only for patients with severe spasticity that cannot tolerate the side effects of or do not benefit from oral baclofen. The injectable drug differs in its composition, making it more effective. Ordinarily, intrathecal baclofen is not considered in ambulatory patients.
Intrathecal inside the central nervous system.
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