What kinds of MS exist

To most physicians dealing with MS and many patients, this illness seems to be a family of closely related disorders. To begin with, a doctor's clinical diagnosis of MS is based on the recognition of symptoms that recur (relapse). The relapsing nature of the disease is unique to MS. Recognition of symptoms that are typically associated with MS makes a neurologist's diagnosis easier.

Relapse appearance of new signs or recurrence of previous signs of MS.

By consensus, MS is usually divided into four different types for the purposes of study: (1) relapsing-remitting MS, (2) secondary progressive MS, (3) primary progressive MS, and (4) relapsing progressive. This does not mean that they have different causes.

Table 1. New MS Diagnostic Criteria

Clinical

Attacks

Objective Lesions

Additional Requirements to Make Diagnosis

>2

>2

Clinical evidence is enough

>2

1

Disseminated in space by MRI or +CSF and two more MRI lesions consistent with MS or additional clinical attack in different site

1

2 or more

Disseminated in time by MRI or second clinical attack

Mono-symptomatic

1

Disseminated in space by MRI or + CSF and two or more MRI lesions consistent with MS and disseminated in time by MRI or second attack

Progressive from start

1

+ CSF and disseminated in space by MRI evidence of three or more T2 brain lesions or two or more cord lesions or four to eight brain and one cord lesions or + VEP and four to eight MS lesions or + VEP and four brain lesions + one cord lesion and disseminated in time by MRI or continued progression for 1 year.

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