Onychomatricoma

Onychomatricoma is a recently described entity, clinically characterized by a thickened, yellow longitudinal nail portion with splinter haemorrhages and a slight overcurvature, consisting of a markedly papillomatous lesion of the matrix covered by normal nail-producing epithelium. Its connective tissue stroma is densely cellular and contains fine collagen fibres. The tumour projections fit into channels in the thickened nail substance that run along the whole length of the nail. After avulsion, the nail substance shows these channels lined with the upper third to half of normal matrix epithelium, exactly as seen on the nail's undersurface after nail avulsion. The exact nature of this lesion is not yet clear; however, human papillomavirus has not been demonstrated.

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