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Figure 3.91. A close-up of the face of the same infant as in Figure 3.90 at the age of 3 weeks again shows the severe growth retardation, sunken cheeks, pointed chin, large mouth, large eyes that have a very alert expression, and large ears. Note the gingival hyperplasia.

Gingival Warts

Figure 3.92. A lateral view of the face of the same infant. Note the sunken face and very large ears in the upper half of the figure. The lower portion of the figure shows the large hands that are seen in these infants. Note the marked loss of subcutaneous tissue and wrinkled, loose skin. Infants with Donohue's syndrome commonly have large hands and feet. At autopsy the infant had cystic ovaries which are typically found in this condition.

Figure 3.92. A lateral view of the face of the same infant. Note the sunken face and very large ears in the upper half of the figure. The lower portion of the figure shows the large hands that are seen in these infants. Note the marked loss of subcutaneous tissue and wrinkled, loose skin. Infants with Donohue's syndrome commonly have large hands and feet. At autopsy the infant had cystic ovaries which are typically found in this condition.

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