Infant Glaucoma

Brushfield Spots

Figure 2.58. Aniridia with cerebellar malformation is an autosomal recessive disorder which seems to be associated with little variability in expression. On the left is a rather complete aniridia with corneal clouding due to glaucoma. On the right is another virtually complete aniridia with minimal iris remnants.

Figure 2.58. Aniridia with cerebellar malformation is an autosomal recessive disorder which seems to be associated with little variability in expression. On the left is a rather complete aniridia with corneal clouding due to glaucoma. On the right is another virtually complete aniridia with minimal iris remnants.

Figure 2.59. This figure shows a typical (inferonasal) isolated iris coloboma related to a failure of fusion of the optic cup at its most anterior extent. All iris structures are intact except in the inferonasal position.

Figure 2.60. This figure demonstrates Brush-field's spots in an infant with brown irides which are pathognomonic for Down syndrome. In contrast, Brushfield's spots in an infant with blue irides is a nonspecific finding of many blue irides.

Figure 2.61. Rieger's syndrome is an autosomal dominant (4q23-q27) disorder with abnormal irides, associated with an abnormal umbilicus and malformed teeth. Abnormal iris stroma is present, and glaucoma is common. Families may exhibit variable expressivity. On the left is an eye with polycoria, dyscoria, and correctopia present at birth. On the right is the same eye several years later demonstrating early glaucoma due to progressive obliteration of the chamber angle by adhesions of the iris to an anterior Schwalbe's line.

Figure 2.62. This figure demonstrates less severe anomalies of the anterior segment. On the left is an eye with dysco-ria and correctopia which was present at birth resembling an iris coloboma due to a small iris adhesion to an anterior Schwalbe's line. On the right is an eye with a central pupil, which is fortuitous since glaucoma is less likely to occur in eyes with cen-

tral pupils.

Eyes With Glaucoma

2.62

Figure 2.63. This figure shows members of a family with autosomal dominant pseudo-Rieger's syndrome which has been associated with an abnormal pituitary or an empty sella in some affected family members. An abnormal iris stroma is present and glaucoma is common. Families may exhibit variable expressivity. On the left is an eye with end stage glaucoma with secondary corneal clouding. On the right is an eye with early glaucoma with abnormal adhesions of the iris to an anterior Schwalbe's line extending 360 degrees.

End Stage Glaucoma

2.63

Eccentric Pupil

Figure 2.64. Anterior segments in members of the same family with pseudo-Rieger's syndrome are shown as in Figure 2.63. On the left is an eye with an eccentric pupil resembling an iris coloboma due to a small iris adhesion to an anterior Schwalbe's line. On the right is an eye with a central pupil which does not have an associated glaucoma.

Figure 2.64. Anterior segments in members of the same family with pseudo-Rieger's syndrome are shown as in Figure 2.63. On the left is an eye with an eccentric pupil resembling an iris coloboma due to a small iris adhesion to an anterior Schwalbe's line. On the right is an eye with a central pupil which does not have an associated glaucoma.

2.65

Megalocornea

Figure 2.65. This infant demonstrates the asymmetrical eye size seen with unilateral glaucoma which is an autosomal recessive disorder. Megalocornea (a constant enlarged corneal diameter present at birth) must be considered in patients with bilateral glaucoma (a corneal enlargment which is progressive up to age 2 years). In megalocornea, the intraocular pressure is not increased. Glaucoma usually presents with excessive tearing, photophobia, and corneal clouding.

Mole Removal

Mole Removal

Moles, warts, and other unsightly irregularities of the skin can be bothersome and even embarrassing. They can be removed naturally... Removing Warts and Moles Naturally! If you have moles, warts, and other skin irregularities that you cannot cover up affecting the way you look, you can have them removed. Doctors can be extremely expensive. Learn the natural ways you can remove these irregularities in the comfort of your own home.

Get My Free Ebook


Post a comment