Beckwith Wiedemann

Macroglosia Pompe Disease Infant

Figure 1.103. Macroglossia in an otherwise normal infant. The most common cause of macroglos-sia is idiopathic hypertrophy of the muscles of the tongue.

Macroglossia Newborns
Figure 1.104. Macroglossia associated with Beckwith-Wiedemann syndrome. These infants have exomphalos (omphalocele or large umbilical hernia), macroglossia, and gigantism (EMG syndrome).

1.105

Beckwith Wiedemann
Figure 1.105. Another infant with Beckwith-Wiedemann syndrome showing the protrusion of the tongue with macroglos-sia. Note the other characteristic finding of a transverse crease of the earlobe.
Adults With Beckwith Wiedemann Syndrome

Figure 1.106. Macroglossia in a 2-month-old infant with Type II glycogen storage disease (Pompe's disease). Macroglossia is also seen in infants with congenital hypothyroidism and hemangioma or lymphangioma of the tongue.

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