Cause Of Rubella Disease

Fetal Malformations Caused Rubella

Figure 2.128. Opisthotonos in an infant with congenital rubella encephalitis. Viral culture from cerebrospinal fluid was positive.

Figure 2.127. Corneal clouding and prominence of left eye due to glaucoma in an infant with congenital rubella. One should suspect glaucoma (buphthalmos) in any infant with a wide or cloudy cornea.

Figure 2.128. Opisthotonos in an infant with congenital rubella encephalitis. Viral culture from cerebrospinal fluid was positive.

Figure 2.129. Adenopathy in an infant with congenital rubella. Enlargement of lymph nodes is uncommon in the neonate, but is described in infants with other viral syndromes and in congenital syphilis where the epitrochlear glands especially are enlarged.

Figure 2.130. Lateral radiograph of the skull in an infant with congenital rubella. Note the very large anterior fontanelle, prominent sutures and poor mineralizaton of the calvaria. Bony abnormalities are seen at birth in up to 80% of infants with congenital rubella. These include the large anterior fontanelle and characteristic "celery stalk appearance." These bony abnormalities also resemble those of other fetal viral infections such as cytomegalovirus.

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