Backgroundsummary 21 Insulin Resistance and PCOS

The role of insulin resistance in the pathogenesis of PCOS has been extensively reviewed in Chapter 24. Briefly, insulin resistance is an intrinsic and virtually universal feature of PCOS. Insulin resistance exists in PCOS independent of obesity, as evidenced by the presence of insulin resistance even in lean women with PCOS (1). In addition, about 50-80% of women with PCOS are obese.

Hence, in PCOS obesity further induces an added burden of insulin resistance and hyperinsulinemia in addition to the component of insulin resistance that is intrinsic to the disorder (2).

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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