Clinical Features of Myoclonus

Super Memory Formula

New Diet for Memory Loss

Get Instant Access

Myoclonus is a brief, jerklike contraction of a single muscle or muscle group that occurs as an isolated event or may occur in a repetitive regular or irregular manner. Myoclonus may be associated with dementias (e.g., Creutzfeldt-Jakob disease, subacute sclerosing panencephalitis, and Alzheimer disease), lipidoses (e.g., Tay-Sachs and Niemann-Pick diseases), leukodystrophies (e.g., Krabbe and Pelizaeus-Merzbacher diseases), cerebellar degenerations (e.g., Ramsay-Hunt syndrome), epilepsy syndromes (e.g., Unverricht-Lundborg disease, Lafora body disease, and neuronal ceroid lipofuscinosis), Friedreich ataxia, hypoxic and other metabolic encephalopathies (e.g., uremic and hepatic), remote effects of cancer (e.g., infantile myoclonus associated with neuroblastoma), exposure to drugs or toxins (e.g., levodopa, lead, mercury, strychnine, methylphenidate, and amphetamines), and a variety of other disorders. Negative myoclonus, or asterixis, manifests as a sudden loss of postural tone, and has been described in various metabolic or toxic encephalopathies and in certain diencephalic lesions. Segmental or spinal myoclonus is characterized by a rhythmic contraction of a group of muscles in a particular segment, such as an arm, a leg, or the abdominal muscles. Examples include palatal myoclonus, ocular myoclonus, and hiccups. Palatal myoclonus has been described in patients with lesions involving the dentato-rubro-olivary pathway (Mollaret triangle) (Sathornsumetee and Stacy in press). [Video Segment 19]

Was this article helpful?

0 0
All About Alzheimers

All About Alzheimers

The comprehensive new ebook All About Alzheimers puts everything into perspective. Youll gain insight and awareness into the disease. Learn how to maintain the patients emotional health. Discover tactics you can use to deal with constant life changes. Find out how counselors can help, and when they should intervene. Learn safety precautions that can protect you, your family and your loved one. All About Alzheimers will truly empower you.

Get My Free Ebook

Post a comment