Summary

Detailed assessments of abnormal motor syndromes in rodents are a challenging but necessary task facing many investigators interested in elucidating pathogenesis and discovering new treatments for movement disorders. Currently a large number of tests are available for motor function, as well as several strategies for selecting the most appropriate tests for specific purposes; but the development of more refined techniques for discriminating among the many different types of movement disorders is still needed.

TABLE 6 Discriminating Ataxia from Dystonia

Ataxia

Dystonia

Morphology Falling

Righting after Falls Muscle Tone Resting Postures Mortality

Clumsiness not due to weakness or superimposed involuntary movement

Imprecise and inaccurate foot placement Rapid

Normal or decreased

Normal

Normal

Twisting pattern movements with sustained abnormal postures

Propelled to side by stiffened or twisting limbs

Slow

Increased

Abnormal

Increased

Acknowledgments

This work was supported by grants from the National Institutes of Health (NS40470 and NS33592).

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The Donts of Treadmill Buying

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Though competitive runners are advised to run on the road, there are several reasons why you should buy treadmills anyway. You might have a family which means that your schedule does not have the flexibility it once had.

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