The primary glomerulopathies are those disorders that affect glomerular structure, function, or both in the absence of a multisystem disorder. The clinical manifestations are predominately the consequence of the glomerular lesion (such as proteinuria, hematuria, and reduced glomerular filtration rate). The combination of clinical manifestations leads to a variety of clinical syndromes. These syndromes include acute glomerulomphritis; rapidly progressive glomerulonephritis; chronic renal failure; the nephrotic syndrome or "asymptomatic" hematuria, proteinuria, or both.
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