Classification Of Infections Occurring In Transplant Patients

Infections related to technical complications* Transplantation of a contaminated allograft, anastomotic leak or stenosis, wound hematoma, intravenous line contamination, iatrogenic damage to the skin, mismanagement of endotracheal tube leading to aspiration, infection related to biliary, urinary, and drainage catheters Infections related to excessive nosocomial hazard Aspergillus species, Legionella species, Pseudomonas aeruginosa, and other gramnegative bacilli, Nocardia asteroides Infections related to particular exposures within the community Systemic mycotic infections in certain geographic areas Histoplasma capsulatum, Coccidioides immitis, Blastomyces dermatitidis, Strongyloides stercoralis Community-acquired opportunistic infection resulting from ubiquitous saphro-phytes in the environment* Cryptococcus neoformans, Aspergillus species, Nocardia asteroides, Pneumocystis carinii Respiratory infections circulating in the community Mycobacterium tuberculosis, influenza, adenoviruses, parainfluenza, respiratory syncytial virus

Infections acquired by the ingestion of contaminated food/water Salmonella species, Listeria monocytogenes Viral infections of particular importance in transplant patients Herpes group viruses, hepatitis viruses, papillomavirus, HIV

*All lead to infection with gram-negative bacilli, Staphylococcus species, and/or Candida species.

*The incidence and severity of these infections and, to a lesser extent, the other infections listed, are related to the net state of immunosuppression present in a particular patient.

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