Figure 1128

Severity of systemic lupus erythematosus (SLE) disease activity during hemodialysis or continuous ambulatory peritoneal dialysis (CAPD). Lupus disease activity generally decreases during dialysis treatment. As assessed by the SLE Disease Activity Index (SLEDAI) [66], the maximal nonrenal SLEDAI decreased during dialysis in 49% of patients, remained stable in 42%, and showed progression in 9%. Despite the fact that immunosuppression was minimized, in 90% of patients cytotoxic drug therapy was discontinued and in 55% the dose of steroids was considerably reduced [65]. In addition, in this analysis no differences were found in disease activity in patients treated with either hemodialysis or CAPD. The maximal nonrenal SLEDAI scores were divided in three groups: 0, no extrarenal disease activity; 1 to 10, moderate extrarenal disease activity; over 10, high extrarenal disease activity.

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