Figure 1130

Lupus disease activity after renal transplantation. Disease activity was assessed in 28 patients with systemic lupus erythematosus (SLE) by calculating the maximal nonrenal SLE Disease Activity Index (SLEDAI) in the time periods before dialysis, during dialysis, and after renal transplantation. The maximal nonrenal SLEDAI scores were divided in three groups: 0, no extrarenal disease activity; 1 to 10, moderate extrarenal disease activity; over 10, high extrarenal disease activity. Note that before dialysis all patients had extrarenal lupus disease activity but that after renal transplantation no patient had high disease activity. These data illustrate that the decrease in disease activity that begins during dialysis treatment continues after renal transplantation. In addition, recurrence of lupus nephritis after renal transplantation is rare [67]. (From Berden [14]; with permission. Data from Nossent et al. [68].)

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