Figure 1149

The clinical manifestations of the tubulointerstitial nephritis in Sjögrens syndrome can vary and depend on localization of the functional impairment. Occasionally, symptoms of tubular dysfunction precede development of symptoms of Sjögrens syndrome. It is unclear what causes these tubular dysfunctions. When the degree of tubulointerstitial damage is not chronic, corticosteroids are beneficial. Glomerular involvement is rare in Sjögrens syndrome. When a glomerulonephritis is present, the patient should be evaluated for the presence of cryoglobulins and existence of systemic lupus ery-thematosus. Reference 95 provides a more detailed description of this subject.

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