Figure 116

A, Relationship between constant serum levels and concomitant renal cortical accumulation of gentamicin after a 6 hour intravenous infusion in rats. The rate of accumulation is expressed in micrograms of aminoglycoside per gram of wet kidney cortex per hour, due to the linear accumulation in function of time. Each point represents one rat whose aminoglycosides were measured in both kidneys at the end of the infusion and the serum levels assayed twice during the infusion [8].

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