Figure 122

Multiple actions of angiotensin. Angiotensin II and some of the other angiotensin II metabolites have a myriad of actions on many different vascular beds and organ systems. Angiotensin II exerts short- and long-term actions, including vasoconstriction and stimulation of aldosterone release. Angiotensin II also interacts with the sympathetic nervous system by facilitating adrenergic transmission and has long-term actions on vascular smooth muscle proliferation by interacting with growth factors. Angiotensin II exerts several important effects on the kidney that contribute to sodium conservation. (Adapted from Navar [3].)


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