Figure 1236

Long-term risks of kidney donation. In a meta-analysis combining 48 studies of the long-term effects of reduced renal mass in humans, no evidence was found of a progressive decline in renal function after a 50% reduction in renal mass. Indeed, a small but statistically significant increase occurred over time in the glomerular filtration rate. A small increase in urine protein excretion occurred; however, the rate of increase per decade was less than that generally considered an abnormal amount of protein excretion, eg, 150 mg/d. A small increase in systolic blood pressure was noted; however, it was not enough to lead to an increase in the incidence of hypertension. Thus, it appears that the long-term risks of kidney donation are very small. Shown are multiple linear regression coefficients and 95% confidence intervals. Failure of the confidence interval to include zero indicates P < 0.05. (From Kasiske and coworkers [12]; with permission.)

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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