Figure 1325

Magnetic resonance imaging of osteonecrosis. Osteonecrosis most commonly affects the femoral head but can affect any weight-bearing bone. The most debilitating complication of renal transplantation, its incidence seems to be decreasing (<10% of transplant recipients). This decrease reflects better management of calcium and bone homeostasis during long-term dialysis and less intense steroid use after transplantation. The pathogenesis of osteonecrosis remains poorly understood, and therapeutic options are limited (pain management while awaiting progression to the need for joint replacement). Magnetic resonance imaging is a sensitive diagnostic method, allowing detection of osteonecrosis at a very early stage [39].

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