Figure 1512

Phagocytosis by macrophages or nearby cells

Apoptosis and oncosis are the two generally recognized forms of cell death. Apoptosis, also known as programmed cell death and cell suicide, is characterized morphologically by cell shrinkage, cell budding forming apoptotic bodies, and phagocytosis by macrophages and nearby cells. In contrast, oncosis, also known as necrosis, necrotic cell death, and cell murder, is characterized morphologically by cell and organelle swelling, plasma membrane bleb-bing, cell lysis, and inflammation. It has been suggested that cell death characterized by cell swelling and lysis not be called necrosis or necrotic cell death because these terms describe events that occur well after the cell has died and include cell and tissue breakdown and cell debris. (From Majno and Joris [4]; with permission.)

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