Figure 154

Exogenous and endogenous chemicals that cause acute renal failure.

Papillae

Phenacetin

Renal vessels NSAIDs ACE inhibitors Cyclosporin A

Interstitium

Cephalosporins Cadmium NSAIDs

Proximal convoluted tubule (S1/S2 segments) Aminoglycosides Cephaloridine Cadmium chloride Potassium dichromate

Renal vessels NSAIDs ACE inhibitors Cyclosporin A

Glomeruli

Interferon-a Gold

Penicillamine

Proximal straight tubule (S3 segment) Cisplatin

Mercuric chloride Dichlorovinyl-L-cysteine

Interstitium

Cephalosporins Cadmium NSAIDs

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