Figure 1615

Potential of in vitro tubulogenesis research. Flow chart indicates relevance of in vitro models of kidney epithelial cell branching tubulogenesis to basic and applied areas of kidney research. While results from such studies provide critical insight into kidney development, this model system might also contribute to the elucidation of mechanisms involved in kidney injury and repair for a number of diseases, including tubular epithelial cell regeneration secondary to acute renal failure. Moreover, these models of branching tubulo-genesis could lead to therapies that utilize tubular engineering as artificial renal replacement therapy [82].

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