Figure 1616

Cellular response to growth factors. Schematic representation of the pleiotrophic effects of growth factors, which share several properties and are believed to be important in the development and morphogenesis of organs and tissues, such as those of the kidney. Among these properties are the ability to regulate or activate numerous cellular signaling responses, including proliferation (mitogenesis), motility (motogenesis), and differentiation (morphogenesis). These characteristics allow growth factors to play critical roles in a number of complex biological functions, including embryogenesis, angiogenesis, tissue regeneration, and malignant transformation [83].

0 0

Post a comment