Figure 1620

Data from the North American Pediatric Renal Transplant Cooperative Study on late first rejection rates by quartiles of maintenance cyclosporine dose at 1 year. The first acute rejection occurred over 1 year after transplantation. Patients not receiving cyclosporine (human leukocyte antigen-identical or those receiving tacrolimus [FK-506]) form a small group. The difference between the rejection rates for the other four groups are not statistically significant. The lowest rate of late first rejection, however, is observed in those patients receiving dosages of cyclosporine over 8.6 mg/kg/d. CsA— cyclosporine; SD—standard deviation. (From Tejani and Sullivan [15]; with permission.)

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