Figure 1624

Data from the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) on the mean change from baseline in standardized height scores in patients with graft function. The height standard deviation score (SDS), or Z score, is the current accepted measurement used to evaluate accelerated growth. The Z score is an attempt to standardize the height deficit of children with renal failure to the height of healthy children. A positive change in Z score (+8 Z), for example, indicates a reduction in height deficit (ie, an acceleration of growth). At transplantation the mean height deficit (Z score or SDS) for all patients was -2.16 standard deviations (SD) below the appropriate age- and gender-adjusted levels. Recipients under 6 years of age at the time of transplantation showed acceleration in linear growth after transplantation at 4 years' follow-up. Children 6 years of age or older at time of transplantation showed no improvement in height deficit at 4 years' follow-up. Z score— patient's height - height at 50% for age and standard deviation of height for age. (From Warady and coworkers [5]; with permission.)

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