Figure 1628

A Finnish study investigating the possible association between growth hormone treatment and acceleration of chronic rejection and late allograft dysfunction in prepubertal children. The most common histologic findings between the eight growth hormone-treated and eight nontreated renal transplantation recipients are scored and compared (matched for age, donor age, human leukocyte antigen, immunosuppression, and renal function) 36 months after transplantation. Improvement in growth was clear during administration of growth hormone, without a negative influence on allograft survival. No significant difference in the amount of lymphocyte infiltration of the allografts between patients and the control group was seen. No acute rejection episodes occurred in the recipients treated with growth hormone but one occurred in the control group. SD—standard deviation. (From Laine and coworkers [29]; with permission.)

0 0

Post a comment