Figure 1631

Data from the 1995 North American Pediatric Renal Transplant Cooperative Study showing that the cumulative risk for first rejection is similar for living donor (LD) and cadaveric donor (CD) recipients in the first few weeks after transplantation. After the first month, however, the cumulative risk for a first rejection is higher for recipients of a CD graft. By the end of the 48th month, 56% of LD recipients and 71% of CD recipients have had at least one rejection episode. Rejections were completely reversed (return to baseline creatinine) in 53% of LD graft recipients, partially reversed (improved graft function but no return to baseline creatinine) in 40%, and resulted in graft failure or death in 4% of cases. In CD, rejection episodes were completely reversed in 49%, partially reversed in 45%, and resulted in graft failure or death in 6%. (From Warady and coworkers [5]; with permission.)

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