Figure 1633

Data from the North American Pediatric Renal Transplant Cooperative Study showing causes of graft failure. Chronic rejection has become the most common cause of graft failure (27.1%). Acute rejection causes up to 18.6% of graft failures. Recurrence of primary disease (focal segmental glomeru-losclerosis) accounts for 6.8% of all failures. Vascular thrombosis continues to cause a significant number of graft failures (12.9%). (From Warady and coworkers [5]; with permission.)

*Four patients have had three graft failures.

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