Figure 1640

Data from the North American Pediatric Renal Transplant Cooperative Study for cadaveric donor renal allografts showing that the lowest graft survival rates occurred in children with focal segmental glomerular sclerosis or congenital nephrotic syndrome (panel A), or hemolytic uremic syndrome (panel B). These rates range from 40% to 58.9%. In patients with focal segmental glomerular sclerosis, graft failure was attributed to disease recurrence in 14 of 81 (17%) patients who received cadaveric donor kidneys. A, The highest graft survival rate correlated with the diagnosis of congenital and structural disease and glomerulonephritis (72.2% and 73.5%, respectively). (From Kashton and coworkers [38]; with permission.)

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