Figure 1739

In these diseases, rapid recurrence leading to graft failure is frequent enough to warrant extreme caution in using living related donors. Even excluding these conditions, the overall rate of recurrence of glomerulonephritis is substantially increased in living related donors, and patients should be made aware of this risk [4]. For familial diseases, the risk of recurrence is even higher (eg, some families with immunoglobulin A disease and hemolytic uremic syndrome). Finally, recurrent glomerulonephritis has been reported in up to 30% of renal isografts, with disease onset between 2 weeks and 16 years after grafting.

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