Figure 178

Several studies have reported an increased incidence of recurrent glomerulonephritis (GN) after renal transplantation in grafts from living related donors. In one study with histologic data available on both donors and recipients, GN recurred in 8.7% of 149 cadaveric grafts compared with 25.8% of 124 living donor grafts [16,17]. The data shown here are from the Eurotransplant Registry. These data demonstrate a substantial excess of recurrent GN causing graft failure in living donor grafts compared with cadaveric grafts from the same centers over the same time period [4]. Up to one third of all the graft failures in grafts from living related donors were due to recurrent disease compared with less than 1 in 10 graft failures in cadaveric transplantations. No difference in recurrence rates was seen in any of the first 5 years after transplantation. GN—glomerulonephritis. (Adapted from Kotanko and coworkers [4].)

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