Figure 1915

Composition of dialysate and replacement fluids used for continuous renal replacement therapy (CRRT). One of the key features of any dialysis method is the manipulation of metabolic balance. In general, this is achieved by altering composition of dialysate or replacement fluid . Most commercially available dialysate and replacement solutions have lactate as the base; however, bicarbonate-based solutions are being utilized more and more [17,18].

Replacement 17 mL/min Prefilter Prefilter

Prepump Prepump

BFR 83 mL/min BFR 117 mL/min

Blood pump BFR 100 mL/min

Blood pump BFR 100 mL/min

Postfilter BFR 100 mL/min

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