Figure 1ds1

Maternal manifestations of preeclampsia. Preeclampsia is a multisystem maternal disorder, with dramatic alterations in heart, kidney, circulation, liver, and brain. Interestingly, all of these abnormalities resolve within a few weeks of delivery.

•I Placental hormones (eg, estrogen, progesterone)

T Circulating endothelial toxins

T Sympathetic nervous system r

•I Placental hormones (eg, estrogen, progesterone)

T Circulating endothelial toxins

T Sympathetic nervous system r

Compensatory responses: X Plasma renin X Aldosterone

Vascular smooth cGMP/cAMP muscle cells

Vascular smooth cGMP/cAMP muscle cells

Compensatory responses: X Plasma renin X Aldosterone

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