Figure 21

Forms of unilateral renal parenchymal diseases related to hypertension. Many unilateral abnormalities, such as congenital malformations, renal agenesis, reflux nephropathy, and stone disease, do not commonly produce hypertension. However, some unilateral lesions can produce blood pressure elevation. Data for each of these are based primarily on demonstrating unilateral secretion of renin and resolution with unilateral nephrectomy. It should be emphasized that unilateral renal disease does not reduce the overall glomerular filtration rate beyond that expected in patients with a solitary kidney. It follows that addi tional reductions in the glomerular filtration rate must reflect bilateral renal injury.

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