Figure 218

Severe crescentic proliferative glomerulonephritis in a patient with Henoch-Schonlein purpura and rapidly progressive glomerulonephritis (Masson trichrome stain). Approximately half of patients with Henoch-Schonlein purpura have mild nephritis with hematuria and proteinuria, but less than a quarter develop renal insufficiency, and rapidly progressive glomerulonephritis is rare. Less than 10% of patients have persistent renal disease that progresses to end-stage renal disease.

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