Figure 227

Necrotizing arteritis involving an interlobular artery in a renal biopsy specimen from a patient with ANCA-positive microscopic polyangiitis (hematoxylin and eosin). There is focal transmural fib-rinoid necrosis with intense perivascular inflammation. This pattern of arteritis is nonspecific, and could be seen, for example, in a patient with polyarteritis nodosa, microscopic polyangiitis, or Wegener's granulomatosis. The presence of ANCA or glomeru-lonephritis in the patient would exclude polyarteritis nodosa.

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