Figure 233

Categorization of patients with crescentic glomerulonephritis with respect to both the immunopathologic category of disease (immune complex versus anti-GBM versus ANCA) and the clinicopathologic expression (glomerulonephritis alone versus Wegener's granulomato-sis versus Goodpasture's syndrome versus other small vessel vasculi-tis) [11]. Note that most patients with ANCA have some expression of systemic vasculitis rather than glomerulonephritis alone. Most patients with Wegener's granulomatosis have C-ANCA/PR3-ANCA but some have P-ANCA/MPO-ANCA. Also note that some patients with anti-GBM and some patients with immune complex disease also are ANCA positive. (Adapted from Jennette [11]).

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