Figure 310

Hypokalemia and magnesium depletion. Hypokalemia and magnesium depletion can occur concurrently in a variety of clinical settings, including diuretic therapy, ketoacidosis, aminoglycoside therapy, and prolonged osmotic diuresis (as with poorly controlled diabetes mellitus). Hypokalemia is also a common finding in patients with congenital magnesium-losing kidney disease. The patient depicted was treated with cisplatin 2 months before presentation. Attempts at oral and intravenous potassium replacement of up to 80 mEq/day were unsuccessful in correcting the hypokalemia. Once serum magnesium was corrected, however, serum potassium quickly normalized [14].

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