Figure 312

Signs of primary systemic amyloidosis in patients during an 11-year study at the Mayo Clinic. The liver was palpable in about one fourth of patients seen within 30 days of diagnosis. Hepatomegaly is due to infiltration of amyloid or congestion from heart failure. The spleen is palpable in only 5% of patients and rarely extends more than 5 cm below the left costal margin. Lymphadenopathy occurs infrequently. (Adapted from Kyle and Gertz [5]; with permission.)

HEMOGLOBIN AND PLATELET VALUES WITHIN 30 DAYS OF DIAGNOSIS OF PRIMARY SYSTEMIC AMYLOIDOSIS, MAYO CLINIC, 1981-1992

Factor

Median

Range

Hemoglobin, g/dL (<10 g/dL in 11%) Platelets, X 109/L (>500 X 109/L in 9%)

0 0

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